Stevens Johnson Syndrome

stevens johnson syndrome (sjs) is an extremely rare disorder characterized by a severe skin reaction to medication

Stevens Johnson Syndrome (SJS) is a rare but serious and potentially life-threatening condition. SJS is defined as a hypersensitivity disorder affecting the skin and mucous membranes. There is a reported incidence of around one case per million people per year.

Stevens Johnson Syndrome is a severe expression of a simple rash known as erythema multiforme. Stevens Johnson Syndrome is also known as erythema multiforme major. It affects all ages and genders including pediatric populations. The most severe form of Stevens Johnson Syndrome is Toxic Epidermal Necrolysis (TENS). Stevens Johnson Syndrome occurs twice as often in men as in women. Most cases of Stevens Johnson Syndrome appear in children and young adults under age 30. Females with Stevens Johnson Syndrome are twice as likely as males to develop , and have an even higher chance if taking a category of drugs known as NSAIDs, non-steroidal anti-inflammatory agents.

stevens johnson syndrome (sjs) facts

  • it appears as target like lesions
  • also known as erythema multiforme major
  • begins with symptoms of non-specific upper respiratory tract infection
  • first 1 to 14 days symptoms of fever, sore throat, chills, headache, malaise, vomiting and diarrhea, and other -like symptoms
  • rash is severe and widespread and typically involves the eyes, mouth, vaginal, urethral, gastrointestinal, respiratory tract and other internal organs
  • skin loss may lead to dehydration, infection or death
  • ocular involvement can include severe onjunctivitis, iritis, conjunctiva and corneal abrasions and corneal perforation

sjs and chantix

A connection between Chantix and the risk of SJS was highlighted in a recent study conducted by the Institute for Safe Medication Practices (ISMP), which used a combination of () adverse event reports and pharmaceutical industry Standardized Medical Queries (SMQ) to gather its data.

In the 4th quarter of 2007 Chantix accounted for 998 serious injuries in the U.S. reported to the , more than any other individual drug in this time period.

The results are even more worrisome because adverse event reporting is voluntary for consumers and health professionals, and as a result it is estimated that only 1 to 10 percent of serious adverse events are reported.

Among the series injuries reported were moderate and severe skin reactions. The notes 338 serious events including hives or swelling of the tongue, face, eyes, lips and other areas. An additional 65 reports of severe side effects included blisters, exfoliation of the skin and lips, and Stevens-Johnson Syndrome.

diagnosed with stevens johnson syndrome?

If you or a loved one have suffered a severe skin reaction while taking a medication, if you have been diagnosed with Stevens Johnson Syndrome, or if you experiencing symptoms associated with Stevens Johnson Syndrome, you may have a claim against the manufacturer.

Please contact us today by filling out the brief questionnaire, or by calling our toll free number (1-800-898-2034) for a free, no-cost no-obligation evaluation of your case.


Latest News

FDA considers expanding indication for Cymbalta; side effects SJS, TEN

A () advisory committee has narrowly voted to recommend that the indication for Eli Lilly’s antidepressant Cymbalta (duloxetine) be expanded to include use as a treatment for chronic musculoskeletal pain. The Anesthetic and Life Support Drugs Advisory Committee also voted that the benefits were minimal but outweighed the risks, which includes a black box warning of suicidality in children, adolescents and young adults; a potential for liver damage; and a risk of developing the rare skin disease Stevens Johnson Syndrome (SJS) and its more serious form, toxic epidermal necrolysis ().

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SJS/TEN survivor sues drug company for $24 million

A New Hampshire jury will decide whether a drug company is liable for $24 million in damages from its prescription anti-inflammatory medication that caused a woman to suffer from a severe reaction that caused painful burns to break out on her skin and internal organs and made her go blind.

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Cause of teen’s TEN remains a mystery

“For me, just being here alive is a story to tell,” Karyl Bell told WNYT-TV. In October 2009, the then-17-year-old unexpectedly developed a rash on her face. Her tongue swelled and she had trouble swallowing and breathing. Her condition quickly worsened. Red, painful blisters broke out on her body. Lesions in her eyes caused her eyes to swell shut. All doctors could tell her worried mother was to sit by as the reaction ran its course and, “hope for the best.”

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