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The Guardian has updated a recent health story about the epilepsy treatment oxcarbazepine, also known as Trileptal. According to the report, two serious adverse reactions have been associated with the medication– Stevens Johnson Syndrome (SJS) and its more severe form, toxic epidermal necrolysis (TEN). The reactions have occurred in both adults and children.
The International Serious Adverse Events Consortium (SAEC) is a global, nonprofit partnership between leading pharmaceutical companies, the FDA and academic institutions. It was organized just more than a year ago. Among its goals, the consortium hopes to identify genetic markers that predict which individuals are at risk for drug-related serious adverse reactions, also known as SAEs.
Natural health products may be all the rage in alternative medicine, however many herbal remedies are linked to serious adverse reactions and potential health risks, according to the January 2009 edition of Health Canada’s Canadian Adverse Reaction Newsletter.
A stimulant-type drug recently was added to the list of medications that may cause Stevens Johnson Syndrome (SJS), a rare but life-threatening condition affecting the skin and mucus membranes, causing the skin to blister and peel away in sheets. MedPage Today reported that drug maker Cephalon has agreed to update the drug’s label to warn of the potential risk of SJS and other serious rashes and hypersensitivity reactions.
“Mommy, take my eyes out,” Ian Milne cried when he was just 3 years old. The Colwood, British Columbia boy had suffered an adverse reaction known as Stevens Johnson Syndrome (SJS), in which the skin blisters and peels away, according to The Windsor Star. Mucus membranes also can be affected, causing painful and debilitating blisters in the body’s orifices such as the mouth and eyes. In more severe cases, dehydration, infection and even death can occur. Many times, long-lasting vision problems, including blindness, can result from lesions in the eyes.
Last month when Kim Oake was bitten by a feral cat while working as an animal control officer in Canada, she was given Clavulin, a common antibiotic to ward off infection. The antibiotic nearly killed her. Her family wants to know why people aren’t told about the serious, life-threatening reaction that could occur by taking common drugs, according to CBC News.
Adverse reactions to antibiotics send more than 140,000 Americans to the emergency room every year, according to a study by the U.S. Centers for Disease Control and reported this month by Natural News.
Researchers centered their focus on antibiotics that were either ingested or injected rather than those that are applied to the skin. Data was pulled from the National Ambulatory Medical Care Survey, National Hospital Ambulatory Medical Care Survey, National Electronic Injury Surveillance System-Cooperative Adverse Drug Event Surveillance project. The data showed that 19 percent of all emergency visits for adverse reactions to drugs were due to antibiotics.
The U.S. Food and Drug Administration is investigating the possibility that phenytoin and fosphenytoin sodium increase the risk of serious skin reactions, such as Stevens Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN), according to FDA MedWatch. Phenytoin and fosphenytoin are used to control tonic-clonic (grand mal) and complex-partial seizures in epilepsy.
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