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	<title>Stevens Johnson Syndrome &#187; Revlimid</title>
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		<title>Drug reactions bring awareness to Stevens Johnson Syndrome</title>
		<link>http://www.sjs-legal.com/news/2008/10/28/drug-reactions-bring-awareness-to-stevens-johnson-syndrome/</link>
		<comments>http://www.sjs-legal.com/news/2008/10/28/drug-reactions-bring-awareness-to-stevens-johnson-syndrome/#comments</comments>
		<pubDate>Tue, 28 Oct 2008 16:11:08 +0000</pubDate>
		<dc:creator>Elizabeth Richards</dc:creator>
				<category><![CDATA[News]]></category>
		<category><![CDATA[Alabama]]></category>
		<category><![CDATA[Arizona]]></category>
		<category><![CDATA[Colorado]]></category>
		<category><![CDATA[Connecticut]]></category>
		<category><![CDATA[drug reactions]]></category>
		<category><![CDATA[FDA]]></category>
		<category><![CDATA[flu]]></category>
		<category><![CDATA[food and drug administration]]></category>
		<category><![CDATA[ibuprofen]]></category>
		<category><![CDATA[Motrin]]></category>
		<category><![CDATA[Revlimid]]></category>
		<category><![CDATA[SJS]]></category>
		<category><![CDATA[Stevens Johnson Syndrome]]></category>
		<category><![CDATA[Stevens Johnson Syndrome Foundation]]></category>
		<category><![CDATA[Tennessee]]></category>
		<category><![CDATA[TENS]]></category>
		<category><![CDATA[toxic epidermal necrolysis]]></category>

		<guid isPermaLink="false">http://www.sjs-legal.com/?p=80</guid>
		<description><![CDATA[New reports from the Food and Drug Administration (FDA) and cancer patients have put Revlimid, an oral medicine given to patients with multiple myeloma, on a list of medications that could possibly cause Stevens Johnson Syndrome when used by itself or mixed with other drugs. Stevens Johnson syndrome is a serious, potentially life-threatening skin disease [...]<p>SOURCE: <a href="http://www.sjs-legal.com">Stevens Johnson Syndrome</a> &rsaquo; <a href="http://www.sjs-legal.com/news/2008/10/28/drug-reactions-bring-awareness-to-stevens-johnson-syndrome/">Drug reactions bring awareness to Stevens Johnson Syndrome</a></p>
]]></description>
			<content:encoded><![CDATA[<p>New reports from the Food and Drug Administration (FDA) and cancer patients have put <a href="http://http://www.revlimid.com/multiple-myeloma/multiple-myeloma-revlimid.aspx">Revlimid</a>, an oral medicine given to patients with multiple myeloma, on a list of medications that could possibly cause <strong><a href="http://www.sjs-legal.com/" title="" rel="external">Stevens Johnson Syndrome</a></strong> when used by itself or mixed with other drugs. <a href="http://www.sjs-legal.com/tag/stevens-johnson-syndrome/" class="st_tag internal_tag" rel="tag" title="Posts tagged with Stevens Johnson Syndrome">Stevens Johnson syndrome</a> is a <strong>serious</strong>, potentially <strong>life-threatening skin disease</strong> that can start with flu-like symptoms and eventually cause a rash that spreads and blisters.<span id="more-80"></span></p>
<p>According to mediafact.com, other <strong>medications</strong> have been linked to <a href="http://www.sjs-legal.com/tag/stevens-johnson-syndrome/" class="st_tag internal_tag" rel="tag" title="Posts tagged with Stevens Johnson Syndrome">Stevens Johnson syndrome</a> including <a href="http://www.beasleyallen.com/focus/Bextra/" title="" rel="external">Bextra</a>, <a href="http://www.beasleyallen.com/focus/Celebrex/" title="" rel="external">Celebrex</a> and Daypro, as well as over-the-counter pain relievers such as Motion, <a href="http://www.sjs-legal.com/tag/ibuprofen/" class="st_tag internal_tag" rel="tag" title="Posts tagged with ibuprofen">Ibuprofen</a>, Children’s Motrin and Advil.</p>
<p>One of the main issues with <a href="http://www.sjs-legal.com/tag/stevens-johnson-syndrome/" class="st_tag internal_tag" rel="tag" title="Posts tagged with Stevens Johnson Syndrome">Stevens Johnson syndrome</a> is the lack of awareness from the patients that are at risk and the doctors that prescribe the medication. In a 2007 press release from <a href="http://http://www.smartbrief.com/news/aaaa/industryBW-detail.jsp?id=428CC602-8616-458E-8C3F-82F19236D0EA">SmartBrief.com</a>, Governor Bill Ritter, Jr., of Colorado, along with the <strong><a href="http://www.sjs-legal.com/tag/stevens-johnson-syndrome/" class="st_tag internal_tag" rel="tag" title="Posts tagged with Stevens Johnson Syndrome">Stevens Johnson Syndrome</a> Foundation</strong>, recognized August 2007 as the designated <strong><a href="http://www.sjs-legal.com/tag/sjs/" class="st_tag internal_tag" rel="tag" title="Posts tagged with SJS">SJS</a> Awareness month</strong>. Joining Colorado in recognizing this month were Arizona, Alabama, Connecticut and Tennessee.</p>
<p>According to the article, <a href="http://www.sjs-legal.com/tag/stevens-johnson-syndrome/" class="st_tag internal_tag" rel="tag" title="Posts tagged with Stevens Johnson Syndrome">Stevens Johnson Syndrome</a> affects more than two million Americans each year and has resulted in more than <strong>140,000 deaths</strong>.</p>
<p>When prescribed a new medication, or even taking over-the-counter medication, educate yourself on <a href="http://www.sjs-legal.com/tag/stevens-johnson-syndrome/" class="st_tag internal_tag" rel="tag" title="Posts tagged with Stevens Johnson Syndrome">Stevens Johnson Syndrome</a> so you can identify the symptoms at the earliest possible stage.</p>
<p>SOURCE: <a href="http://www.sjs-legal.com">Stevens Johnson Syndrome</a> &rsaquo; <a href="http://www.sjs-legal.com/news/2008/10/28/drug-reactions-bring-awareness-to-stevens-johnson-syndrome/">Drug reactions bring awareness to Stevens Johnson Syndrome</a></p>
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		<title>FDA finds link between Revlimid and skin diseases</title>
		<link>http://www.sjs-legal.com/news/2008/10/10/fda-finds-link-between-revlimid-and-skin-diseases/</link>
		<comments>http://www.sjs-legal.com/news/2008/10/10/fda-finds-link-between-revlimid-and-skin-diseases/#comments</comments>
		<pubDate>Fri, 10 Oct 2008 21:37:26 +0000</pubDate>
		<dc:creator>Kurt Niland</dc:creator>
				<category><![CDATA[News]]></category>
		<category><![CDATA[Celgene]]></category>
		<category><![CDATA[drug reactions]]></category>
		<category><![CDATA[FDA]]></category>
		<category><![CDATA[lenalidomide]]></category>
		<category><![CDATA[Revlimid]]></category>
		<category><![CDATA[side effects]]></category>
		<category><![CDATA[SJS]]></category>
		<category><![CDATA[Stevens Johnson Syndrome]]></category>
		<category><![CDATA[TENS]]></category>
		<category><![CDATA[toxic epidermal necrolysis]]></category>

		<guid isPermaLink="false">http://www.sjs-legal.com/?p=75</guid>
		<description><![CDATA[The FDA’s post-market safety review has uncovered a link between lenalidomide (marketed as the drug Revlimid) and serious skin reactions, including Stevens Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN). 
The FDA approved Celgene Corp.’s Revlimid in December 2005 to treat a bone marrow disorder. It was later approved for use in treatment of multiple [...]<p>SOURCE: <a href="http://www.sjs-legal.com">Stevens Johnson Syndrome</a> &rsaquo; <a href="http://www.sjs-legal.com/news/2008/10/10/fda-finds-link-between-revlimid-and-skin-diseases/">FDA finds link between Revlimid and skin diseases</a></p>
]]></description>
			<content:encoded><![CDATA[<p>The <strong>FDA’s</strong> <a href="http://www.fda.gov/cder/dsn/2008_summer/postmarketing.htm#lenalidomide">post-market safety review </a>has uncovered a link between <strong>lenalidomide </strong>(marketed as the drug <strong>Revlimid</strong>) and serious skin <strong>reactions</strong>, including <strong><a href="http://www.sjs-legal.com/" title="" rel="external">Stevens Johnson Syndrome</a> </strong>(<strong><a href="http://www.sjs-legal.com/tag/sjs/" class="st_tag internal_tag" rel="tag" title="Posts tagged with SJS">SJS</a></strong>) and <strong><a href="http://www.sjs-legal.com/toxic-epidermal-necrolysis-syndrome/" title="" rel="external">toxic epidermal necrolysis</a> </strong>(<strong>TEN</strong>). <span id="more-75"></span></p>
<p>The <strong>FDA</strong> approved <strong>Celgene</strong> Corp.’s <strong>Revlimid</strong> in December 2005 to treat a bone marrow disorder. It was later approved for use in treatment of multiple myeloma, a type of blood cancer. Earlier this month, <strong>Revlimid</strong> appeared on a list of approximately twenty drugs under investigation by the <strong>FDA</strong> for possible safety hazards. No details about the specific concerns were made available at that time.</p>
<p>From the drug’s approved use in 2005 to January 23, 2008, the <strong>FDA</strong> received 14 reports of <strong>serious skin reactions</strong> following <strong>Revlimid</strong> therapy. <strong>Three deaths</strong> occurred among the 14 patients who displayed either <strong><a href="http://www.sjs-legal.com/tag/sjs/" class="st_tag internal_tag" rel="tag" title="Posts tagged with SJS">SJS</a></strong> or <strong>TEN</strong>, although progression of cancer is suspected in one of the fatalities.</p>
<p>The estimated incidence of <strong><a href="http://www.sjs-legal.com/tag/sjs/" class="st_tag internal_tag" rel="tag" title="Posts tagged with SJS">SJS</a></strong>/<strong>TEN</strong> is 1 to 2 persons per million annually. According to Brian Gill, a spokesman for the manufacturer of <strong>Revlimid</strong>, approximately 60 thousand people have been treated with the drug. Individuals with <strong><a href="http://www.sjs-legal.com/tag/sjs/" class="st_tag internal_tag" rel="tag" title="Posts tagged with SJS">SJS</a></strong> normally have 10-30 percent of their body surface area affected by the disorder. <strong><a href="http://www.sjs-legal.com/tag/sjs/" class="st_tag internal_tag" rel="tag" title="Posts tagged with SJS">SJS</a></strong>-related mortality is estimated to be between 1-3%. People with <strong>TEN</strong> normally suffer an infliction of more than 30% of their body’s surface area. Mortality ranges anywhere from 10-70%, according to the <strong>FDA</strong>.</p>
<p><strong>Revlimid</strong> currently comes with warnings of other serious hazards, including <a href="http://www.paxilandpregnancy.com/paxil-birth-defects/birth-defects/" title="" rel="external">birth defects</a> and blood clots and is distributed, sold, and used with great restriction. The drug’s labeling will be updated to include reports of skin reactions and doctors are strongly advised to discontinue use in patients that develop skin irritations while taking <strong>Revlimid</strong>.</p>
<p>SOURCE: <a href="http://www.sjs-legal.com">Stevens Johnson Syndrome</a> &rsaquo; <a href="http://www.sjs-legal.com/news/2008/10/10/fda-finds-link-between-revlimid-and-skin-diseases/">FDA finds link between Revlimid and skin diseases</a></p>
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